Interesting to see that 3pcb.com do all their drilling first, then etching. We tried that when making double-sided boards and 50% of the time it worked ok, and 50% of the time it was a massive fail.
3pcb.com run a 24-hour PCB factory. Check out those manufacturing start times - they're running right through the night. And what a nice touch, showing where you board manufacturing is up to, at any point, through their website.
Then again, I guess a professional PCB fab house isn't lining up sheets of toner-transfer paper, by hand, to make their circuit boards. Or at least, I'd rather hope they weren't!